Diagnostic Challenges: Asperger's vs. ADHD

Research question: What are the key diagnostic challenges and differentiating factors between Asperger's syndrome and ADHD in clinical practice?

Plain-language summary

Understanding the differences between what was once known as Asperger's Syndrome and ADHD can be tricky because recent changes in how we diagnose conditions mean Asperger's is now part of the broader Autism Spectrum Disorder (ASD). Research suggests that while there are distinct characteristics, there can also be overlapping traits, making a clear distinction challenging in some cases.

Key findings

Studies cited (4)

  1. ADHD and autism: differential diagnosis or overlapping traits? A selective review — Taurines R, Schwenck C, Westerwald E (2012, Attention deficit and hyperactivity disorders, review)

    DOI: 10.1007/s12402-012-0086-2

  2. Plasma and red blood cell n3 fatty acids correlate positively with the WISC-R verbal and full-scale intelligence quotients and inversely with Conner's parent-rated ADHD index t-scores in children with high functioning autism and Asperger's syndrome. — Beata Joanna Kozielec - Oracka, Y. Min, A. Bhullar (2022, Prostaglandins, Leukotrienes and Essential Fatty Acids, observational)

    Findings of the fatty acid status of people with autism spectrum disorders have been incongruent perhaps because of the diversity of the condition. A cross-sectional design study was used to  investigated fatty acid levels and relationships between fatty acids, and cognition and behaviour in a homogenous group of children with autism spectrum disorder. Children with Asperger's syndrome (AS) /high functioning autism (n = 44) and healthy siblings (n = 17) were recruited from the Diagnostic and Therapeutic Centre for Children with Autism, Warsaw, Poland. In the AS group, plasma phosphatidylcholin

  3. The investigation and differential diagnosis of Asperger syndrome in adults — Lehnhardt FG, Gawronski A, Pfeiffer K (2013, Deutsches Arzteblatt international, other)

    DOI: 10.3238/arztebl.2013.0755 PMCID: PMC3849991

  4. Use of Gilliam Asperger's disorder scale in differentiating high and low functioning autism and ADHD — Mayes SD, Calhoun SL, Murray MJ (2011, Psychological reports, other)

    DOI: 10.2466/04.10.15.PR0.108.1.3-13

Based on 4 curated peer-reviewed studies (from 11 matches across PubMed, Semantic Scholar, and Europe PMC).